About Dr. Priska Darani, Ph.D.

Dr. Priska Darani has had a lifelong passion for understanding how diet regulates metabolism and contributes to health in both humans and animals. Priska grew up on a dairy farm in Eastern Ontario before attending the University of Guelph in 2005 to complete a B.Sc. in Animal Biology with a focus on nutrition. While at Guelph, she worked at the Arkell Poultry and Equine Research Station where she assisted with daily care of the horses. In 2012, she received an M.Sc. for OMAFRA-funded research on how altering the amino acid balance of lactating cow rations can affect milk production and composition. In 2016, she completed her Ph.D. degree focusing on nutritional regulation of insulin sensitivity and using mathematical models to predict metabolic responses.

 
 
 
Research Publications Cited By
Regulation of chylomicron secretion: focus on post-assembly mechanisms.
C Xiao, P Stahel, GF Lewis.
Cellular and molecular gastroenterology and hepatology 7 (3), 487-501, 2019.
71
The atherogenic dyslipidemia complex and novel approaches to cardiovascular disease prevention in diabetes.
P Stahel, C Xiao, RA Hegele, GF Lewis.
Canadian Journal of Cardiology 34 (5), 595-604, 2018.
54
Recent advances in triacylglycerol mobilization by the gut.
C Xiao, P Stahel, AL Carreiro, KK Buhman, GF Lewis.
Trends in Endocrinology & Metabolism 29 (3), 151-163, 2018.
49
Oral glucose mobilizes triglyceride stores from the human intestine.
C Xiao, P Stahel, AL Carreiro, YH Hung, S Dash, I Bookman, KK Buhman, ....
Cellular and Molecular Gastroenterology and Hepatology 7 (2), 313-337, 2019.
35
Glucose and GLP-2 (Glucagon-Like Peptide-2) mobilize intestinal triglyceride by distinct mechanisms.
P Stahel, C Xiao, X Davis, P Tso, GF Lewis.
Arteriosclerosis, thrombosis, and vascular biology 39 (8), 1565-1573, 2019.
26
Emerging role of lymphatics in the regulation of intestinal lipid mobilization.
C Xiao, P Stahel, A Nahmias, GF Lewis.
Frontiers in Physiology 10, 1604, 2020.
25
Use of dietary feather meal to induce histidine deficiency or imbalance in dairy cows and effects on milk composition.
P Stahel, NG Purdie, JP Cant.
Journal of dairy science 97 (1), 439-445, 2014.
25
Of the milk sugars, galactose, but not prebiotic galacto-oligosaccharide, improves insulin sensitivity in male Sprague-Dawley rats.
P Stahel, JJ Kim, C Xiao, JP Cant.
PloS one 12 (2), e0172260, 2017.
22
Effects of intranasal insulin on endogenous glucose production in insulin‐resistant men.
C Xiao, S Dash, P Stahel, GF Lewis.
Diabetes, Obesity and Metabolism 20 (7), 1751-1754, 2018.
21
Polygenic risk for hypertriglyceridemia can mimic a major monogenic mutation.
P Stahel, C Xiao, RA Hegele, GF Lewis.
Annals of Internal Medicine 167 (5), 360-361, 2017.
19
Role of the gut in diabetic dyslipidemia.
P Stahel, C Xiao, A Nahmias, GF Lewis.
Frontiers in Endocrinology 11, 116, 2020.
17
Supranutritional selenium intake from enriched milk casein impairs hepatic insulin sensitivity via attenuated IRS/PI3K/AKT signaling and decreased PGC-1α expression in male ….
P Stahel, JJ Kim, SRL Cieslar, JM Warrington, C Xiao, JP Cant.
The Journal of nutritional biochemistry 41, 142-150, 2017.
17
Glycemia and atherosclerotic cardiovascular disease: exploring the gap between risk marker and risk factor.
A Nahmias, P Stahel, C Xiao, GF Lewis.
Frontiers in cardiovascular medicine 7, 100, 2020.
14
Effects of intranasal insulin on triglyceride-rich lipoprotein particle production in healthy men.
C Xiao, S Dash, P Stahel, GF Lewis.
Arteriosclerosis, Thrombosis, and Vascular Biology 37 (9), 1776-1781, 2017.
13
A mechanistic model of intermittent gastric emptying and glucose-insulin dynamics following a meal containing milk components.
P Stahel, JP Cant, JAR MacPherson, H Berends, MA Steele.
PloS one 11 (6), e0156443, 2016.
13
Selenized milk casein in the diet of BALB/c nude mice reduces growth of intramammary MCF-7 tumors.
JM Warrington, JJM Kim, P Stahel, SRL Cieslar, RA Moorehead, ....
BMC cancer 13, 1-11, 2013.
13
Intranasal glucagon acutely increases energy expenditure without inducing hyperglycaemia in overweight/obese adults.
P Stahel, SJ Lee, SK Sud, A Floh, S Dash.
Diabetes, Obesity and Metabolism 21 (6), 1357-1364, 2019.
12
Glucagon‐like peptide‐2 mobilizes lipids from the intestine by a systemic nitric oxide‐independent mechanism.
C Xiao, P Stahel, C Morgantini, A Nahmias, S Dash, GF Lewis.
Diabetes, Obesity and Metabolism 21 (11), 2535-2541, 2019.
11
GLP-1 (glucagon-like peptide-1) is physiologically relevant for chylomicron secretion beyond its known pharmacological role.
A Nahmias, P Stahel, L Tian, C Xiao, GF Lewis.
Arteriosclerosis, Thrombosis, and Vascular Biology 41 (6), 1893-1900, 2021.
10
Evaluation of the specific effects of intranasal glucagon on glucose production and lipid concentration in healthy men during a pancreatic clamp.
S Dash, C Xiao, P Stahel, K Koulajian, A Giacca, GF Lewis.
Diabetes, Obesity and Metabolism 20 (2), 328-334, 2018.
9
Multi-organ coordination of lipoprotein secretion by hormones, nutrients and neural networks.
P Stahel, C Xiao, A Nahmias, L Tian, GF Lewis.
Endocrine Reviews 42 (6), 815-838, 2021.
7
Evaluation of the genetic association between adult obesity and neuropsychiatric disease.
P Stahel, A Nahmias, SK Sud, SJ Lee, A Pucci, A Yousseif, A Youseff, ....
Diabetes 68 (12), 2235-2246, 2019.
7
Phenotypic and genetic analysis of an adult cohort with extreme obesity.
P Stahel, SK Sud, SJ Lee, T Jackson, DR Urbach, A Okrainec, JP Allard, ....
International Journal of Obesity 43 (10), 2057-2065, 2019.
7
Control of intestinal lipoprotein secretion by dietary carbohydrates.
P Stahel, C Xiao, GF Lewis.
Current Opinion in Lipidology 29 (1), 24-29, 2018.
7
Parameters of abomasal emptying and glucose-insulin dynamics in Holstein-Friesian calves at 2 ages and 2 levels of milk replacer intake.
P Stahel, JAR MacPherson, H Berends, MA Steele, JP Cant.
Journal of Dairy Science 100 (6), 5068-5072, 2017.
6
Effect of replacing lactose with fat in milk replacer on abomasal emptying and glucose–insulin kinetics in male dairy calves.
P Stahel, H Berends, LN Leal, J Martin-Tereso.
Applied Animal Science 35 (6), 586-595, 2019.
4
Investigation of the role of enteric blood flow in mediating GLP-2 stimulation of triglyceride mobilization and chylomicron secretion in the human intestine.
C Xiao, P Stahel, S Dash, C Morgantini, GF Lewis.
Atherosclerosis Supplements 32, 29, 2018.
4
Hypothalamic miR-1983 Targets Insulin Receptor β and the Insulin-mediated miR-1983 Increase Is Blocked by Metformin.
JA Chalmers, PS Dalvi, N Loganathan, EK McIlwraith, L Wellhauser, ....
Endocrinology 163 (1), bqab241, 2022.
2
Assessment of lipid response to acute olanzapine administration in healthy adults.
A Nahmias, P Stahel, S Dash.
Endocrinology, Diabetes & Metabolism 3 (2), e00119, 2020.
2
Glucagon-like peptide-2 acutely enhances chylomicron secretion in humans without mobilizing cytoplasmic lipid droplets.
MM Syed-Abdul, P Stahel, A Zembroski, L Tian, C Xiao, A Nahmias, ....
The Journal of Clinical Endocrinology & Metabolism 108 (5), 1084-1092, 2023.
1
Glucagon-like peptide-2 mobilization of intestinal lipid does not require canonical enterocyte chylomicron synthetic machinery.
MM Syed-Abdul, P Stahel, L Tian, C Xiao, A Nahmias, GF Lewis.
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2022.
1
Enteral glucose, absorbed and metabolized, potently enhances mesenteric lymph flow in chow-and high-fat-fed rats.
L Tian, MM Syed-Abdul, P Stahel, GF Lewis.
American Journal of Physiology-Gastrointestinal and Liver Physiology 323 (4 …, 2022.
ABSTRACT 成人肥満と精神神経疾患との遺伝的関連性の評価.
P Stahel, A Nahmias, SK Sud, SJ Lee, A Pucci, A Yousseif, A Youseff, ....
Diabetes: a journal of the American Diabetes Association 13 (3), 33-35, 2020.
Evaluation of the Acute Effects of Intranasal Glucagon on Energy Balance in Overweight/Obese Adults.
P Stahel, SJ Lee, S Sud, AA Floh, S Dash.
Canadian Journal of Diabetes 42 (5), S37, 2018.
Phenotypic and Genetic Analysis of Adults with Extreme Obesity.
P Stahel, S Sud, SJ Lee, A Bassett, A Paterson, S Sockalingam, S Dash.
Canadian Journal of Diabetes 42 (5), S37, 2018.
Oral Glucose Mobilizes Triglyceride Stores from the Human Intestine.
P Stahel, C Xiao, AL Carreiro, YH Hung, A Zembroski, S Dash, ....
Atherosclerosis Supplements 32, 21, 2018.
Regulation of Chylomicron Secretion: Focus on Post Assembly.
C Xiao, P Stahel, GF Lewis.
.
Evaluation of the Effect of Intranasal Glucagon on Endogenous Glucose Production.
S Dash, C Xiao, K Koulajian, GF Lewis.
DIABETES 65, A483-A483, 2016.
A mechanistic model of intermittent gastric emptying and glucose-insulin dynamics following a meal containing milk components.
JP Cant, MA Steele, P Stahel, JAR MacPherson, H Berends.
.
Effects of selenized casein and carbohydrate components of milk on insulin sensitivity in rats.
P Stahel.
University of Guelph, 2016.
Decreasing the solids-non-fat: fat ratio of milk with dietary feather meal in dairy cows..
P Stahel, NG Purdie, JP Cant.
CANADIAN JOURNAL OF ANIMAL SCIENCE 91 (3), 505-505, 2011.
135 AMPK Wars: the VMH Strikes Back, Return of the PVH 137 Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf’s Footprints.
AR Hamoud, L Weaver, DE Stec, TD Hinds Jr, C Xiao, P Stahel, ....
.